In need of a jump here

I am in a black mood and there's no end in sight. It's been going on roughly since Monday, when I had a nasty crash from missing Wellbutrin on Saturday, and although there have been intervening recoveries and plateaus I've been getting steadily more confused, depressed and hopeless. And now it's been 5 days from the missed dose. This has to be related to Effexor. Right?